Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 12/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | STAT1 | P42224 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26603266 | 1.00 | PARG (0.57) | PARGALDH1A1HIF1AAKR1C3GAA | |
| SCHEMBL26603305 | 0.93 | PARG (0.57) | PARGALDH1A1HIF1AGAAUSP2 | |
| SCHEMBL30709126 | 0.93 | PARG (0.57) | PARGALDH1A1HIF1AGAAUSP2 | |
| SCHEMBL30709080 | 0.92 | PARG (0.60) | PARGALDH1A1HIF1AUSP2LMNA | |
| SCHEMBL26603361 | 0.92 | PARG (0.60) | PARGALDH1A1HIF1AUSP2LMNA | |
| SCHEMBL30709107 | 0.91 | HIF1A (0.55) | PARGHIF1AGAAUSP2LMNA | |
| SCHEMBL26603319 | 0.91 | HIF1A (0.55) | PARGHIF1AGAAUSP2LMNA | |
| SCHEMBL30709142 | 0.90 | ALDH1A1 (0.68) | ALDH1A1AKR1C3GAANPC1RAB9A | |
| SCHEMBL26603443 | 0.90 | ALDH1A1 (0.68) | ALDH1A1AKR1C3GAANPC1RAB9A | |
| SCHEMBL26603402 | 0.90 | ALDH1A1 (0.66) | PARGALDH1A1HIF1AAKR1C3USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903563-A | GPCR modulators and uses thereof | 北京昌平实验室 | 2023-10-20 | — | — | CN | disclosed |