Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | PARG | Q86W56 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | STAT1 | P42224 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30709080 | 0.93 | PARG (0.60) | ALDH1A1PARGHIF1ASMN1; SMN2LMNA | |
| SCHEMBL26603361 | 0.93 | PARG (0.60) | ALDH1A1PARGHIF1ASMN1; SMN2LMNA | |
| SCHEMBL26603484 | 0.90 | PARG (0.62) | ALDH1A1PARGHIF1ASMN1; SMN2LMNA | |
| SCHEMBL26603266 | 0.90 | PARG (0.57) | ALDH1A1PARGHIF1ASMN1; SMN2LMNA | |
| SCHEMBL30709059 | 0.90 | PARG (0.57) | ALDH1A1PARGHIF1ASMN1; SMN2LMNA | |
| SCHEMBL30709163 | 0.90 | HIF1A (0.67) | ALDH1A1PARGHIF1ASMN1; SMN2LMNA | |
| SCHEMBL30709089 | 0.90 | PARG (0.61) | ALDH1A1PARGHIF1ASMN1; SMN2LMNA | |
| SCHEMBL26603441 | 0.90 | HIF1A (0.67) | ALDH1A1PARGHIF1ASMN1; SMN2LMNA | |
| SCHEMBL30709112 | 0.90 | PARG (0.61) | ALDH1A1PARGHIF1ASMN1; SMN2LMNA | |
| SCHEMBL26603242 | 0.90 | HIF1A (0.67) | ALDH1A1PARGHIF1ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023202582-A1 | GPCR REGULATOR AND USE THEREOF | 北京昌平实验室 | 2023-10-26 | — | — | WO | disclosed |