Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | NPC1 | O15118 | 3/20 | 0.72 |
| ▸ | RAB9A | P51151 | 3/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA7 | P43166 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL63811 | 0.98 | MAPT (0.75) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL29632743 | 0.95 | MAPT (0.72) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL2952068 | 0.91 | MEN1 (0.68) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11125474 | 0.90 | RAB9A (0.66) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL26134425 | 0.88 | MEN1 (0.65) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL21288599 | 0.88 | KMT2A (0.64) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL5415723 | 0.88 | MEN1 (0.74) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL24230270 | 0.86 | KMT2A (0.62) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL15437144 | 0.86 | MEN1 (0.65) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL12973297 | 0.86 | PTPN1 (0.63) | MAPTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023204642-A1 | PROTEIN KINASE INHIBITOR AND USE THEREOF | (주)메디톡스 | 2023-10-26 | — | — | WO | disclosed |
| WO-2022086284-A1 | PROTEIN KINASE INHIBITOR AND USE THEREOF | (주)메디톡스 | 2022-04-28 | — | — | WO | disclosed |