Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP4 | P49662 | 1/20 | 0.38 |
| ▸ | CASP5 | P51878 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30605623 | 0.92 | HRH4 (0.46) | HRH4OPRM1OPRK1OPRL1KMT2A | |
| SCHEMBL26604064 | 0.90 | HRH4 (0.42) | HRH4RAF1BRAFRETSYK | |
| SCHEMBL30605629 | 0.90 | HRH4 (0.42) | HRH4RAF1BRAFRETSYK | |
| SCHEMBL26604109 | 0.88 | HRH4 (0.47) | HRH4RETIGF1R | |
| SCHEMBL26604107 | 0.88 | HRH4 (0.47) | HRH4RETIGF1R | |
| SCHEMBL30605608 | 0.87 | HRH4 (0.41) | HRH4OPRM1OPRK1OPRL1RAF1 | |
| SCHEMBL9085486 | 0.82 | HRH4 (0.56) | HRH4KMT2AMEN1RAF1BRAF | |
| SCHEMBL30605627 | 0.80 | HRH4 (0.51) | HRH4KMT2AMEN1RAF1BRAF | |
| SCHEMBL30605601 | 0.80 | HRH4 (0.51) | HRH4OPRM1OPRK1OPRL1KMT2A | |
| SCHEMBL26604138 | 0.77 | RAF1 (0.48) | HRH4OPRM1OPRK1OPRL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023204642-A1 | PROTEIN KINASE INHIBITOR AND USE THEREOF | (주)메디톡스 | 2023-10-26 | — | — | WO | disclosed |