Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 7/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.50 |
| ▸ | PIM1 | P11309 | 5/20 | 0.50 |
| ▸ | ITK | Q08881 | 5/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.50 |
| ▸ | CDC7 | O00311 | 4/20 | 0.50 |
| ▸ | DAPK3 | O43293 | 4/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.50 |
| ▸ | PAK4 | O96013 | 4/20 | 0.50 |
| ▸ | PRKACA | P17612 | 4/20 | 0.50 |
| ▸ | CDK2 | P24941 | 4/20 | 0.50 |
| ▸ | FLT3 | P36888 | 4/20 | 0.50 |
| ▸ | CDK8 | P49336 | 4/20 | 0.50 |
| ▸ | CLK2 | P49760 | 4/20 | 0.50 |
| ▸ | GSK3B | P49841 | 4/20 | 0.50 |
| ▸ | PRKX | P51817 | 4/20 | 0.50 |
| ▸ | JAK3 | P52333 | 4/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.50 |
| ▸ | MAP4K2 | Q12851 | 4/20 | 0.50 |
| ▸ | STK3 | Q13188 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11653016 | 0.92 | MEN1 (0.46) | LCKAURKBPIM1ITKMAPK8 | |
| SCHEMBL26604133 | 0.90 | CDC7 (0.54) | LCKAURKBPIM1ITKMAPK8 | |
| SCHEMBL26604125 | 0.89 | LCK (0.47) | LCKAURKBPIM1ITKMAPK8 | |
| SCHEMBL9083981 | 0.85 | MEN1 (0.56) | AURKBITKMAPK8CDC7DAPK3 | |
| SCHEMBL26604140 | 0.82 | MCHR1 (0.50) | LCKAURKBPIM1ITKMAPK8 | |
| SCHEMBL26604151 | 0.80 | MERTK (0.44) | LCKAURKBPIM1ITKMAPK8 | |
| SCHEMBL935044 | 0.79 | CDC7 (0.46) | LCKAURKBPIM1ITKMAPK8 | |
| SCHEMBL30605621 | 0.78 | CCNT1 (0.47) | LCKAURKBPIM1ITKMAPK8 | |
| SCHEMBL26604070 | 0.77 | EGFR (0.51) | LCKAURKBPIM1ITKMAPK8 | |
| SCHEMBL3451258 | 0.77 | CDC7 (0.58) | LCKAURKBPIM1ITKMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023204642-A1 | PROTEIN KINASE INHIBITOR AND USE THEREOF | (주)메디톡스 | 2023-10-26 | — | — | WO | disclosed |