Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 4/20 | 0.44 |
| ▸ | TYRO3 | Q06418 | 3/20 | 0.42 |
| ▸ | GAS6 | Q14393 | 2/20 | 0.42 |
| ▸ | LCK | P06239 | 6/20 | 0.41 |
| ▸ | CDK9 | P50750 | 5/20 | 0.41 |
| ▸ | ITK | Q08881 | 5/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.41 |
| ▸ | CDC7 | O00311 | 3/20 | 0.41 |
| ▸ | PIM1 | P11309 | 3/20 | 0.41 |
| ▸ | PRKACA | P17612 | 3/20 | 0.41 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | HIPK2 | Q9H2X6 | 3/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | FLT3 | P36888 | 3/20 | 0.41 |
| ▸ | CDK7 | P50613 | 2/20 | 0.41 |
| ▸ | INSR | P06213 | 2/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26604152 | 0.80 | LCK (0.50) | MERTKTYRO3LCKCDK9ITK | |
| SCHEMBL26604125 | 0.79 | LCK (0.47) | MERTKLCKCDK9ITKAURKB | |
| SCHEMBL26604133 | 0.77 | CDC7 (0.54) | MERTKTYRO3LCKCDK9ITK | |
| SCHEMBL10555993 | 0.77 | MERTK (0.44) | MERTKTYRO3GAS6CDK9SYK | |
| SCHEMBL26604140 | 0.73 | MCHR1 (0.50) | MERTKLCKCDK9ITKAURKB | |
| SCHEMBL11653016 | 0.73 | MEN1 (0.46) | TYRO3LCKCDK9ITKAURKB | |
| SCHEMBL4819595 | 0.72 | CDC7 (0.47) | CDK9CDC7PIM1PRKACACDK2 | |
| SCHEMBL4819069 | 0.70 | KCNH3 (0.51) | CDK9CDC7PIM1PRKACACDK2 | |
| SCHEMBL29750608 | 0.69 | CYP2D6 (0.64) | CDK9CDC7PIM1PRKACACDK2 | |
| SCHEMBL26965066 | 0.69 | CYP2D6 (0.64) | CDK9CDC7PIM1PRKACACDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023204642-A1 | PROTEIN KINASE INHIBITOR AND USE THEREOF | (주)메디톡스 | 2023-10-26 | — | — | WO | disclosed |