Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.34 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26611134 | 0.83 | CHRM2 (0.46) | CHRM2CHRM1CHRM3GPR119HSD11B1 | |
| SCHEMBL30662884 | 0.83 | CHRM2 (0.46) | CHRM2CHRM1CHRM3GPR119HSD11B1 | |
| SCHEMBL26604392 | 0.82 | CHRM2 (0.45) | CHRM2CHRM1CHRM3GPR119HSD11B1 | |
| SCHEMBL30662893 | 0.82 | CHRM2 (0.45) | CHRM2CHRM1CHRM3GPR119HSD11B1 | |
| SCHEMBL26610918 | 0.81 | CHRM2 (0.43) | CHRM2CHRM1CHRM3GPR119DPP4 | |
| SCHEMBL30662889 | 0.81 | CHRM2 (0.43) | CHRM2CHRM1CHRM3GPR119DPP4 | |
| SCHEMBL26610917 | 0.81 | CHRM2 (0.43) | CHRM2CHRM1CHRM3GPR119DPP4 | |
| SCHEMBL30662888 | 0.75 | CHRM2 (0.38) | CHRM2CHRM1CHRM3GPR119HSD11B1 | |
| SCHEMBL26604342 | 0.75 | CHRM2 (0.38) | CHRM2CHRM1CHRM3GPR119HSD11B1 | |
| SCHEMBL26611154 | 0.73 | CHRM2 (0.37) | CHRM2CHRM1CHRM3GPR119HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023205701-A1 | MACROCYCLIC HETEROCYCLES AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2023-10-26 | — | — | WO | disclosed |