Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | PREP | P48147 | 2/20 | 0.35 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26604392 | 1.00 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HSD11B1GPR119 | |
| SCHEMBL30662884 | 0.86 | CHRM2 (0.46) | CHRM2CHRM1CHRM3HSD11B1GPR119 | |
| SCHEMBL26611134 | 0.86 | CHRM2 (0.46) | CHRM2CHRM1CHRM3HSD11B1GPR119 | |
| SCHEMBL30662888 | 0.86 | CHRM2 (0.38) | CHRM2CHRM1CHRM3HSD11B1GPR119 | |
| SCHEMBL26604342 | 0.86 | CHRM2 (0.38) | CHRM2CHRM1CHRM3HSD11B1GPR119 | |
| SCHEMBL26610917 | 0.82 | CHRM2 (0.43) | CHRM2CHRM1CHRM3HSD11B1GPR119 | |
| SCHEMBL30662889 | 0.82 | CHRM2 (0.43) | CHRM2CHRM1CHRM3HSD11B1GPR119 | |
| SCHEMBL26610918 | 0.82 | CHRM2 (0.43) | CHRM2CHRM1CHRM3HSD11B1GPR119 | |
| SCHEMBL26604483 | 0.82 | CHRM2 (0.42) | CHRM2CHRM1CHRM3HSD11B1GPR119 | |
| SCHEMBL12094654 | 0.80 | GPR119 (0.50) | CHRM2CHRM1CHRM3HSD11B1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4511128-A1 | MACROCYCLIC HETEROCYCLES AND USES THEREOF | Kumquat Biosciences Inc. (US) | 2025-02-26 | — | — | EP | disclosed |
| CN-119095849-A | Macrocyclic heterocycles and uses thereof | 金橘生物科技公司 | 2024-12-06 | — | — | CN | disclosed |
| WO-2023205701-A1 | MACROCYCLIC HETEROCYCLES AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2023-10-26 | — | — | WO | disclosed |