Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | F13A1 | P00488 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | TGM1 | P22735 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1189968 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2CYP2C19NPC1RAB9AMEN1 | |
| SCHEMBL6524693 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2CYP2C19NPC1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL716733 | 0.99 | SMN1; SMN2 (0.65) | SMN1; SMN2CYP2C19NPC1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL2514584 | 0.99 | SMN1; SMN2 (0.65) | SMN1; SMN2CYP2C19NPC1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL6175666 | 0.99 | SMN1; SMN2 (0.65) | SMN1; SMN2CYP2C19NPC1RAB9AMEN1 | |
| Acetic Acid SCHEMBL2495069 | 0.96 | SMN1; SMN2 (0.62) | SMN1; SMN2CYP2C19NPC1RAB9AMEN1 | |
| Trifluoroacetic Acid SCHEMBL952417 | 0.92 | SMN1; SMN2 (0.58) | SMN1; SMN2CYP2C19NPC1RAB9AMEN1 | |
| SCHEMBL764193 | 0.92 | SMN1; SMN2 (0.60) | SMN1; SMN2CYP2C19NPC1RAB9AMEN1 | |
| SCHEMBL654999 | 0.92 | SMN1; SMN2 (0.60) | SMN1; SMN2CYP2C19NPC1RAB9AMEN1 | |
| SCHEMBL12791106 | 0.92 | SMN1; SMN2 (0.60) | SMN1; SMN2CYP2C19NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2623593-B1 | NOVEL AMINOTRANSFERASE AND GENE ENCODING SAME, AND USE OF THE AMINOTRANSFERASE AND THE GENE | KANEKA CORP (JP) | 2017-07-12 | — | — | EP | claimed |
| EP-2684953-B1 | MODIFIED AMINOTRANSFERASE, GENE THEREOF, AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUND USING SAME | KANEKA CORP (JP) | 2017-06-28 | — | — | EP | claimed |
| EP-2623595-B1 | NOVEL TRANSAMINASE SHOWING HIGH ACTIVITY FOR GLUTAMIC ACID, GENE ENCODING SAME, AND METHOD FOR UTILIZATION THEREOF | KANEKA CORP (JP) | 2016-11-02 | — | — | EP | claimed |
| US-9481870-B2 | Nucleic acid encoding a polypeptide having aminotransferase activity, vectors and host cells comprising the nucleic acid | KANEKA CORPORATION (JP) | 2016-11-01 | — | — | US | claimed |
| CN-103534353-B | Modification type aminopherase, its gene and utilize their manufacture method of optical activity amino-compound | 株式会社钟化 | 2016-08-17 | — | — | CN | claimed |
| CN-103140580-B | Aminotransferase, gene encoding the same, and method for using the same | KANEKA CORP. (JP) | 2016-06-01 | — | — | CN | claimed |
| CN-103534350-B | Aminotransferase exhibiting high activity for glutamic acid, gene encoding the same, and method for using the same | KANEKA CORP. (JP) | 2016-03-09 | — | — | CN | claimed |
| US-9029113-B2 | Modified aminotransferase, gene thereof, and method for producing optically active amino compound using same | KANEKA CORPORATION (JP) | 2015-05-12 | — | — | US | claimed |
| CN-103534353-A | Modified aminotransferase, gene thereof, and method for producing optically active amino compound using same | KANEKA CORP | 2014-01-22 | — | — | CN | claimed |
| CN-103534350-A | Novel aminotransferase exhibiting high activity for glutamic acid, gene encoding the same, and method for using the same | KANEKA CORP | 2014-01-22 | — | — | CN | claimed |
| EP-2684953-A1 | MODIFIED AMINOTRANSFERASE, GENE THEREOF, AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUND USING SAME | Kaneka Corporation (JP) | 2014-01-15 | — | — | EP | claimed |
| US-20140004575-A1 | MODIFIED AMINOTRANSFERASE, GENE THEREOF, AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUND USING SAME | KANEKA CORPORATION (JP) | 2014-01-02 | — | — | US | claimed |
| US-20130210092-A1 | Novel Transaminase, Gene Encoding the Same, and Method Using Them | KANEKA CORPORATION (JP) | 2013-08-15 | — | — | US | claimed |
| EP-2623595-A1 | NOVEL TRANSAMINASE SHOWING HIGH ACTIVITY FOR GLUTAMIC ACID, GENE ENCODING SAME, AND METHOD FOR UTILIZATION THEREOF | Kaneka Corporation (JP) | 2013-08-07 | — | — | EP | claimed |
| EP-2623593-A1 | NOVEL AMINOTRANSFERASE AND GENE ENCODING SAME, AND USE OF THE AMINOTRANSFERASE AND THE GENE | Kaneka Corporation (JP) | 2013-08-07 | — | — | EP | claimed |
| US-20130196389-A1 | NOVEL TRANSAMINASE EXHIBITING HIGH ACTIVITY FOR GLUTAMIC ACID, GENE ENCODING SAME, AND METHOD FOR USING THEM | KANEKA CORPORATION (JP) | 2013-08-01 | — | — | US | claimed |
| CN-103140580-A | Novel aminotransferase, gene encoding the same, and method for using the same | KANEKA CORP | 2013-06-05 | — | — | CN | claimed |
| EP-4598535-A2 | INHIBITORS OF SPNS2 AND USES THEREOF | New York University (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-1993022283-A1 | PROCESS FOR THE MANUFACTURE OF (S)-3-AMINO-1-SUBSTITUTED-PYRROLIDINES | WARNER-LAMBERT COMPANY (US) | 1993-11-11 | — | — | WO | disclosed |
| US-5250704-A | Process for the manufacture of (S)-3-amino-1-substituted-pyrrolidines | WARNER-LAMBERT COMPANY (US) | 1993-10-05 | — | — | US | disclosed |