SCHEMBL26607604

SCHEMBL26607604

Cc1ccc(C2C[C@H]3CNC[C@H]3C2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.44
CHRNA4 P43681 1/20 0.44
ESRRB O95718 1/20 0.40
ESRRG P62508 1/20 0.40
MAPT P10636 2/20 0.36
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
HTR2B P41595 1/20 0.36
MAP1LC3B Q9GZQ8 1/20 0.35
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
KCNH2 Q12809 1/20 0.34
KDM4E B2RXH2 1/20 0.34
SLC18A3 Q16572 1/20 0.34
ADCY5 O95622 1/20 0.34
P2RY14 Q15391 1/20 0.34
HTR3A P46098 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26607602 1.00 CHRNB2 (0.44) CHRNB2CHRNA4ESRRBESRRGMAPT
SCHEMBL16994772 0.87 CHRNB2 (0.50) CHRNB2CHRNA4ESRRBESRRGMAPT
Hydrochloric Acid SCHEMBL29090976 0.85 ESRRB (0.50) CHRNB2CHRNA4ESRRBESRRGMAPT
SCHEMBL18722791 0.78 SLC18A3 (0.50) CHRNB2CHRNA4MAPTCHRNB4CHRNA3
SCHEMBL16608244 0.78 SLC18A3 (0.50) CHRNB2CHRNA4MAPTCHRNB4CHRNA3
SCHEMBL14704853 0.78 SLC18A3 (0.50) CHRNB2CHRNA4MAPTCHRNB4CHRNA3
SCHEMBL16608333 0.78 SLC18A3 (0.50) CHRNB2CHRNA4MAPTCHRNB4CHRNA3
Hydrochloric Acid SCHEMBL26607617 0.78 KDM1A (0.44) CHRNB2CHRNA4HTR2AHTR2CHTR2B
Hydrochloric Acid SCHEMBL26607615 0.78 KDM1A (0.44) CHRNB2CHRNA4HTR2AHTR2CHTR2B
Hydrochloric Acid SCHEMBL31323882 0.76 HTR2C (0.60) CHRNB2CHRNA4HTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4512807-A1 BICYCLOAMINE CARBOXAMIDE DERIVATIVE Sumitomo Pharma Co., Ltd. (JP) 2025-02-26 EP disclosed
CN-119053606-A Bicyclic carboxamide derivatives 住友制药株式会社 2024-11-29 CN disclosed
WO-2023204291-A1 BICYCLOAMINE CARBOXAMIDE DERIVATIVE 住友ファーマ株式会社 2023-10-26 WO disclosed