Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444302 | 0.80 | NPC1 (0.41) | PTGDR2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL7444364 | 0.74 | MAPT (0.40) | PTGDR2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1514834 | 0.73 | NOTUM (0.43) | PTGDR2MAPTALDH1A1HPGD | |
| SCHEMBL16952943 | 0.73 | NOTUM (0.36) | PTGDR2 | |
| SCHEMBL7432560 | 0.71 | NR1H4 (0.36) | MAPTMEN1KMT2AALDH1A1GLA | |
| SCHEMBL8447500 | 0.70 | CYP2C9 (0.43) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL16962218 | 0.69 | HCRTR1 (0.33) | — | |
| SCHEMBL16884624 | 0.69 | PARP1 (0.41) | — | |
| SCHEMBL5001048 | 0.69 | NOTUM (0.40) | PTGDR2ALDH1A1HPGD | |
| SCHEMBL5001042 | 0.69 | NOTUM (0.40) | PTGDR2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129654-A1 | NOVEL ANTAGONISTS OF THE GLUCAGON RECEPTOR | Metabasis Therapeutics, Inc. (US) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008098244-A1 | NOVEL ANTAGONISTS OF THE GLUCAGON RECEPTOR | METABASIS THERAPEUTICS, INC. (US) | 2008-08-14 | — | — | WO | disclosed |