Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16962218 | 0.85 | HCRTR1 (0.33) | NOTUMHCRTR1HCRTR2PDK2PDK4 | |
| SCHEMBL1514834 | 0.83 | NOTUM (0.43) | NOTUMHCRTR1HCRTR2PDK2PDK4 | |
| SCHEMBL16958908 | 0.82 | HCRTR1 (0.32) | NOTUMHCRTR1HCRTR2PDK2PDK4 | |
| SCHEMBL16884624 | 0.81 | PARP1 (0.41) | SLC6A4 | |
| SCHEMBL30280912 | 0.79 | DRD2 (0.47) | PDK2PDK4DRD2 | |
| SCHEMBL28339895 | 0.78 | PDK2 (0.37) | PDK2PDK4DRD2 | |
| SCHEMBL5001042 | 0.78 | NOTUM (0.40) | NOTUMHCRTR1HCRTR2SLC6A4PTGDR2 | |
| SCHEMBL5001048 | 0.78 | NOTUM (0.40) | NOTUMHCRTR1HCRTR2SLC6A4PTGDR2 | |
| SCHEMBL818793 | 0.77 | HTR2C (0.45) | SLC6A4HTR2C | |
| SCHEMBL4392864 | 0.76 | PTGDR2 (0.44) | NOTUMPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |