Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31716611 | 0.85 | KDM4E (0.65) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL26611257 | 0.84 | KDM4E (0.46) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL15230641 | 0.80 | KDM4E (0.71) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL15068509 | 0.80 | KDM4E (0.56) | KDM4EALDH1A1POLBTDP1MAPT | |
| SCHEMBL15068790 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL16797787 | 0.77 | KDM4E (0.44) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL20985955 | 0.75 | KDM4E (0.53) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL26611368 | 0.75 | KDM4E (0.40) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL14912238 | 0.75 | KDM4E (0.53) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL31716041 | 0.75 | KDM4E (0.49) | KDM4EALDH1A1POLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023203174-A1 | HETEROCYCLIC CULLIN RING UBIQUITIN LIGASE COMPOUNDS AND USES THEREOF | PROXYGEN GMBH (AT) | 2023-10-26 | — | — | WO | disclosed |
| WO-2023203174-A1 | HETEROCYCLIC CULLIN RING UBIQUITIN LIGASE COMPOUNDS AND USES THEREOF | PROXYGEN GMBH (AT) | 2023-10-26 | — | — | WO | disclosed |