SCHEMBL26611237

SCHEMBL26611237

Cc1cccc(C)c1Cl.OBO

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
CYP3A4 P08684 1/20 0.42
CHRM1 P11229 1/20 0.42
ALOX15 P16050 1/20 0.42
MAOA P21397 1/20 0.42
TBXA2R P21731 1/20 0.42
ADRA1A P35348 1/20 0.42
HTR2B P41595 1/20 0.42
CYP2A6 P11509 2/20 0.41
CYP1A2 P05177 1/20 0.41
TRPA1 O75762 2/20 0.40
TSHR P16473 2/20 0.40
ATM Q13315 2/20 0.40
ACHE P22303 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CD44 P16070 1/20 0.35
GABRA1 P14867 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL144551 0.88
SCHEMBL1317463 0.85 CYP2A6 (0.47) ALDH1A1CYP3A4CHRM1ALOX15MAOA
SCHEMBL4755295 0.85 CYP2A6 (0.47) ALDH1A1CYP3A4CHRM1ALOX15MAOA
SCHEMBL1697347 0.77 TRPA1 (0.57) ALDH1A1CYP3A4CHRM1CYP2A6CYP1A2
Methyl Alcohol SCHEMBL28438797 0.76 TSHR (0.50) ALDH1A1CYP3A4HTR2BCYP2A6CYP1A2
Hypochlorous Acid SCHEMBL28661376 0.76 TSHR (0.50) ALDH1A1CYP3A4HTR2BCYP2A6CYP1A2
SCHEMBL546021 0.76
SCHEMBL38652649 0.76
O-Xylene SCHEMBL931223 0.76 TSHR (0.71) ALDH1A1CYP3A4CYP2A6CYP1A2TRPA1
SCHEMBL28351 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4267591-A2 ORGANOMETALLIC COMPOUNDS Umicore AG & Co. KG (DE) 2023-11-01 EP disclosed
WO-2022136049-A2 ORGANOMETALLIC COMPOUNDS UMICORE AG & CO. KG (DE) 2022-06-30 WO disclosed