Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 10/20 | 0.78 |
| ▸ | ALK | Q9UM73 | 10/20 | 0.56 |
| ▸ | INSR | P06213 | 6/20 | 0.56 |
| ▸ | IGF1R | P08069 | 5/20 | 0.56 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.54 |
| ▸ | ROS1 | P08922 | 1/20 | 0.52 |
| ▸ | MET | P08581 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26611935 | 0.96 | EGFR (0.77) | EGFRALKINSRIGF1RPTK2 | |
| SCHEMBL26612240 | 0.93 | EGFR (0.76) | EGFRALKINSRIGF1RPTK2 | |
| SCHEMBL26612255 | 0.90 | EGFR (0.77) | EGFRALKINSRIGF1RMET | |
| SCHEMBL26611721 | 0.89 | EGFR (0.77) | EGFRALKINSRIGF1RPTK2 | |
| SCHEMBL26612235 | 0.89 | EGFR (0.76) | EGFRALKINSRIGF1RMET | |
| SCHEMBL26611716 | 0.88 | EGFR (0.74) | EGFRALKINSRIGF1RMET | |
| SCHEMBL21847014 | 0.88 | EGFR (1.00) | EGFRALKPTK2ROS1MET | |
| SCHEMBL26611707 | 0.85 | EGFR (0.75) | EGFRALKINSRIGF1RMET | |
| SCHEMBL26611888 | 0.83 | EGFR (0.79) | EGFRALKINSRIGF1RROS1 | |
| SCHEMBL21847006 | 0.83 | EGFR (1.00) | EGFRALKPTK2ROS1MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640246-B1 | N2,N4-DIPHENYLPYRIMIDINE-2,4-DIAMINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF CANCER | KOREA RES INST CHEMICAL TECH (KR) | 2023-11-01 | — | — | EP | claimed |