Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 10/20 | 0.77 |
| ▸ | IGF1R | P08069 | 4/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | ALK | Q9UM73 | 9/20 | 0.55 |
| ▸ | INSR | P06213 | 3/20 | 0.55 |
| ▸ | MET | P08581 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26611707 | 0.96 | EGFR (0.75) | EGFRIGF1RKCNH2ALKINSR | |
| SCHEMBL26612240 | 0.92 | EGFR (0.76) | EGFRIGF1RALKINSRMET | |
| SCHEMBL26611766 | 0.91 | EGFR (0.76) | EGFRIGF1RALKINSR | |
| SCHEMBL26611468 | 0.90 | EGFR (0.78) | EGFRIGF1RALKINSRMET | |
| SCHEMBL26612235 | 0.90 | EGFR (0.76) | EGFRIGF1RKCNH2ALKINSR | |
| SCHEMBL26611923 | 0.89 | EGFR (0.76) | EGFRIGF1RALKINSR | |
| SCHEMBL26611716 | 0.87 | EGFR (0.74) | EGFRIGF1RALKINSRMET | |
| SCHEMBL21846970 | 0.87 | EGFR (1.00) | EGFRMET | |
| SCHEMBL26611935 | 0.85 | EGFR (0.77) | EGFRIGF1RALKINSRMET | |
| SCHEMBL26611782 | 0.83 | EGFR (0.73) | EGFRIGF1RKCNH2ALKINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640246-B1 | N2,N4-DIPHENYLPYRIMIDINE-2,4-DIAMINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF CANCER | KOREA RES INST CHEMICAL TECH (KR) | 2023-11-01 | — | — | EP | claimed |