Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 7/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 6/20 | 0.40 |
| ▸ | HTR2A | P28223 | 5/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30619211 | 1.00 | ALDH1A1 (0.42) | ALDH1A1CHRM2OPRM1DDB1CRBN | |
| SCHEMBL11978254 | 0.88 | HTR2B (0.43) | ALDH1A1CHRM2OPRM1DDB1CRBN | |
| SCHEMBL16169051 | 0.81 | HTR2B (0.46) | ALDH1A1CHRM2OPRM1DDB1CRBN | |
| SCHEMBL6662085 | 0.78 | ALDH1A1 (0.44) | ALDH1A1CHRM2OPRM1DDB1CRBN | |
| SCHEMBL3540268 | 0.78 | ALDH1A1 (0.44) | ALDH1A1CHRM2OPRM1DDB1CRBN | |
| SCHEMBL15517107 | 0.78 | HTR2B (0.49) | ALDH1A1CHRM2OPRM1DDB1CRBN | |
| SCHEMBL30850112 | 0.77 | HTR2B (0.42) | ALDH1A1CHRM2OPRM1DDB1CRBN | |
| SCHEMBL24424025 | 0.77 | HTR2B (0.58) | ALDH1A1CHRM2OPRM1DDB1CRBN | |
| SCHEMBL31238892 | 0.77 | HTR2B (0.58) | ALDH1A1CHRM2OPRM1DDB1CRBN | |
| SCHEMBL29585627 | 0.77 | HTR2B (0.58) | ALDH1A1CHRM2OPRM1DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4511368-A2 | CCR4 ANTAGONISTS | ChemoCentryx, Inc. (US) | 2025-02-26 | — | — | EP | disclosed |
| US-20230382894-A1 | CCR4 ANTAGONISTS | CHEMOCENTRYX, INC. | 2023-11-30 | — | — | US | disclosed |
| WO-2023205618-A2 | CCR4 ANTAGONISTS | CHEMOCENTRYX, INC. (US) | 2023-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382894-A1 | CCR4 ANTAGONISTS | CCR4, CCR1, CCR3 | ALDH1A1 2323/4885CHRM2 106/4885OPRM1 139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.