Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 13/20 | 0.73 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.68 |
| ▸ | ALK | Q9UM73 | 6/20 | 0.59 |
| ▸ | INSR | P06213 | 5/20 | 0.59 |
| ▸ | IGF1R | P08069 | 4/20 | 0.59 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.57 |
| ▸ | AURKA | O14965 | 1/20 | 0.57 |
| ▸ | ROS1 | P08922 | 1/20 | 0.57 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26612109 | 0.92 | EGFR (0.73) | EGFRALKINSRIGF1RLRRK2 | |
| SCHEMBL26611806 | 0.91 | EGFR (0.77) | EGFRZAP70ALKINSRIGF1R | |
| SCHEMBL26611884 | 0.91 | EGFR (0.77) | EGFRZAP70ALKINSRIGF1R | |
| SCHEMBL26611761 | 0.90 | EGFR (0.73) | EGFRZAP70ALKINSRIGF1R | |
| SCHEMBL26611961 | 0.90 | EGFR (0.72) | EGFRALKINSRIGF1RLRRK2 | |
| SCHEMBL26611568 | 0.90 | EGFR (0.74) | EGFRALKINSRIGF1RLRRK2 | |
| SCHEMBL26612137 | 0.88 | ALK (0.72) | EGFRZAP70ALKINSRIGF1R | |
| SCHEMBL26612055 | 0.88 | EGFR (0.75) | EGFRALKINSRIGF1RLRRK2 | |
| SCHEMBL26611456 | 0.87 | EGFR (0.74) | EGFRZAP70ALKINSRIGF1R | |
| SCHEMBL26611614 | 0.86 | ALK (0.62) | EGFRALKINSRIGF1RLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640246-B1 | N2,N4-DIPHENYLPYRIMIDINE-2,4-DIAMINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF CANCER | KOREA RES INST CHEMICAL TECH (KR) | 2023-11-01 | — | — | EP | claimed |