Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 12/20 | 0.72 |
| ▸ | INSR | P06213 | 10/20 | 0.72 |
| ▸ | IGF1R | P08069 | 9/20 | 0.72 |
| ▸ | EGFR | P00533 | 7/20 | 0.65 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.64 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.64 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.61 |
| ▸ | AURKA | O14965 | 1/20 | 0.61 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.61 |
| ▸ | JAK2 | O60674 | 1/20 | 0.61 |
| ▸ | STK10 | O94804 | 1/20 | 0.61 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.61 |
| ▸ | SLC34A2 | O95436 | 1/20 | 0.61 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.61 |
| ▸ | ABL1 | P00519 | 1/20 | 0.61 |
| ▸ | CD74 | P04233 | 1/20 | 0.61 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.61 |
| ▸ | LCK | P06239 | 1/20 | 0.61 |
| ▸ | FYN | P06241 | 1/20 | 0.61 |
| ▸ | FES | P07332 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26611568 | 0.94 | EGFR (0.74) | ALKINSRIGF1REGFRLRRK2 | |
| SCHEMBL26612055 | 0.92 | EGFR (0.75) | ALKINSRIGF1REGFRLRRK2 | |
| SCHEMBL26611456 | 0.91 | EGFR (0.74) | ALKINSRIGF1REGFRLRRK2 | |
| SCHEMBL26611923 | 0.90 | EGFR (0.76) | ALKINSRIGF1REGFR | |
| SCHEMBL26611721 | 0.89 | EGFR (0.77) | ALKINSRIGF1REGFRLRRK2 | |
| SCHEMBL26611614 | 0.89 | ALK (0.62) | ALKINSRIGF1REGFRLRRK2 | |
| SCHEMBL26611925 | 0.89 | EGFR (0.75) | ALKINSRIGF1REGFRLRRK2 | |
| SCHEMBL26612109 | 0.88 | EGFR (0.73) | ALKINSRIGF1REGFRLRRK2 | |
| SCHEMBL26611766 | 0.88 | EGFR (0.76) | ALKINSRIGF1REGFR | |
| SCHEMBL26612033 | 0.88 | EGFR (0.73) | ALKINSRIGF1REGFRLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640246-B1 | N2,N4-DIPHENYLPYRIMIDINE-2,4-DIAMINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF CANCER | KOREA RES INST CHEMICAL TECH (KR) | 2023-11-01 | — | — | EP | claimed |