Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 2/20 | 0.57 |
| ▸ | IDO1 | P14902 | 7/20 | 0.52 |
| ▸ | TDO2 | P48775 | 6/20 | 0.47 |
| ▸ | IDO2 | Q6ZQW0 | 6/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26614284 | 0.89 | APAF1 (0.59) | APAF1IDO1TDO2IDO2EGFR | |
| SCHEMBL30639106 | 0.88 | APAF1 (0.48) | APAF1IDO1TDO2IDO2EGFR | |
| SCHEMBL26860163 | 0.88 | APAF1 (0.48) | APAF1IDO1TDO2IDO2EGFR | |
| SCHEMBL26855813 | 0.85 | APAF1 (0.52) | APAF1IDO1TDO2IDO2EGFR | |
| SCHEMBL26614184 | 0.85 | APAF1 (0.48) | APAF1IDO1TDO2IDO2EGFR | |
| SCHEMBL30639077 | 0.85 | APAF1 (0.48) | APAF1IDO1TDO2IDO2EGFR | |
| SCHEMBL30639091 | 0.83 | APAF1 (0.61) | APAF1IDO1TDO2IDO2EGFR | |
| SCHEMBL26614118 | 0.83 | APAF1 (0.61) | APAF1IDO1TDO2IDO2EGFR | |
| SCHEMBL26614232 | 0.82 | APAF1 (0.57) | APAF1IDO1TDO2IDO2EGFR | |
| SCHEMBL30639101 | 0.77 | APAF1 (0.67) | APAF1IDO1TDO2IDO2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023211977-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | VISCIENT BIO, INC. (US) | 2023-11-02 | — | — | WO | disclosed |