Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 9/20 | 0.40 |
| ▸ | TDO2 | P48775 | 9/20 | 0.40 |
| ▸ | IDO2 | Q6ZQW0 | 9/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26614178 | 0.90 | ADORA2A (0.44) | APAF1IDO1TDO2IDO2MAPK14 | |
| SCHEMBL30639084 | 0.90 | ADORA2A (0.44) | APAF1IDO1TDO2IDO2MAPK14 | |
| SCHEMBL26614087 | 0.87 | IDO1 (0.50) | APAF1IDO1TDO2IDO2MEN1 | |
| SCHEMBL30639062 | 0.87 | IDO1 (0.50) | APAF1IDO1TDO2IDO2MEN1 | |
| SCHEMBL30639058 | 0.86 | APAF1 (0.53) | APAF1IDO1TDO2IDO2MEN1 | |
| SCHEMBL26614131 | 0.86 | APAF1 (0.53) | APAF1IDO1TDO2IDO2MEN1 | |
| SCHEMBL26614226 | 0.83 | APAF1 (0.49) | APAF1IDO1TDO2IDO2MEN1 | |
| SCHEMBL31382855 | 0.83 | APAF1 (0.49) | APAF1IDO1TDO2IDO2MEN1 | |
| SCHEMBL30639068 | 0.81 | APAF1 (0.47) | APAF1IDO1TDO2IDO2MEN1 | |
| SCHEMBL26614176 | 0.81 | APAF1 (0.47) | APAF1IDO1TDO2IDO2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023211977-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | VISCIENT BIO, INC. (US) | 2023-11-02 | — | — | WO | disclosed |