SCHEMBL26616634

SCHEMBL26616634

CO[Si](CC(=O)C(=O)OCC(F)(F)F)(OC)OC

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.39
ELANE P08246 1/20 0.33
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
KMT2A Q03164 1/20 0.32
HSD17B10 Q99714 1/20 0.32
FABP7 O15540 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26616686 0.79 HTT (0.41) HTTELANEMEN1ALDH1A1TSHR
SCHEMBL26616612 0.76 ALDH1A1 (0.39) MEN1ALDH1A1TSHRKMT2AHSD17B10
SCHEMBL1143909 0.72 HTT (0.59) HTTELANEMEN1ALDH1A1TSHR
SCHEMBL30980015 0.71 HTT (0.48) HTTELANEMEN1ALDH1A1TSHR
SCHEMBL26616641 0.70 SLC1A3 (0.30)
SCHEMBL26616384 0.70 HTT (0.39) HTTELANEMEN1ALDH1A1TSHR
SCHEMBL26616439 0.69 HTT (0.47) HTTELANEMEN1ALDH1A1TSHR
SCHEMBL4797496 0.69 HTT (0.50) HTTMEN1ALDH1A1TSHRKMT2A
SCHEMBL4672613 0.69 HTT (0.50) HTTELANEMEN1ALDH1A1TSHR
SCHEMBL22114834 0.68 HTT (0.45) HTTALDH1A1FABP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230340266-A1 SILICON-CONTAINING COMPOSITION AND METHOD FOR MANUFACTURING SEMICONDUCTOR SUBSTRATE JSR CORPORATION (JP) 2023-10-26 US disclosed