Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MASP2 | O00187 | 1/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.36 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2276872 | 0.64 | ALDH1A1 (0.59) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20677809 | 0.64 | ALDH1A1 (0.52) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7113519 | 0.64 | KDM4E (0.39) | KDM4EHTR2B | |
| Hydrochloric Acid SCHEMBL31596380 | 0.63 | MAPT (0.57) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13050232 | 0.63 | ALDH1A1 (0.46) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13050704 | 0.63 | ALDH1A1 (0.46) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7473764 | 0.63 | ALDH1A1 (0.42) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2674802 | 0.62 | HTR2B (0.55) | KDM4ENPC1RAB9AKMT2AHTR2B | |
| SCHEMBL1298956 | 0.62 | PARP1 (0.50) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6756134 | 0.62 | NPC1 (0.59) | KDM4ENPC1RAB9AKMT2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948652-A1 | GLUCOKINASE ACTIVATORS | Array Biopharma, Inc. (US) | 2008-07-30 | — | — | EP | claimed |
| WO-2007053345-A1 | GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC. (US) | 2007-05-10 | — | — | WO | claimed |