SCHEMBL26617216

SCHEMBL26617216

O=C(NCc1cccc[n+]1[O-])c1cccc(-c2ccc(Cl)cc2)c1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ EPHX2 P34913 1/20 0.49
▸ NR1H4 Q96RI1 1/20 0.49
▸ SUCNR1 Q9BXA5 2/20 0.48
▸ SCN2A Q99250 3/20 0.47
▸ SCN10A Q9Y5Y9 3/20 0.47
▸ KAT6A Q92794 1/20 0.47
▸ UTS2R Q9UKP6 5/20 0.46
▸ CFD P00746 1/20 0.45
▸ ACLY P53396 1/20 0.45
▸ NPC1 O15118 1/20 0.44
▸ ALDH1A1 P00352 1/20 0.44
▸ POLB P06746 1/20 0.44
▸ ALOX12 P18054 1/20 0.44
▸ HTT P42858 1/20 0.44
▸ RAB9A P51151 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ SERPINE1 P05121 1/20 0.44
▸ SENP1 Q9P0U3 1/20 0.43
▸ ERN1 O75460 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26617213 0.93 EPHX2 (0.56) EPHX2NR1H4CFDALDH1A1SMN1; SMN2
SCHEMBL26617195 0.92 EPHX2 (0.47) EPHX2NR1H4KAT6ACFDNPC1
SCHEMBL26704136 0.91 MEN1 (0.50) EPHX2NR1H4CFDSENP1ERN1
SCHEMBL26617194 0.91 RXRA (0.48) EPHX2NR1H4KAT6ACFDACLY
SCHEMBL26617245 0.89 BCL2L1 (0.48) EPHX2NR1H4CFDSMN1; SMN2ERN1
SCHEMBL26617227 0.89 AURKA (0.49) EPHX2NR1H4KAT6ACFDSENP1
SCHEMBL26617205 0.89 EPHX2 (0.48) EPHX2NR1H4UTS2RCFDALDH1A1
SCHEMBL26617196 0.89 DRD4 (0.48) EPHX2NR1H4UTS2RCFDACLY
SCHEMBL26617231 0.89 EPHX2 (0.46) EPHX2NR1H4UTS2RCFDRAB9A
SCHEMBL26617249 0.88 EPHX2 (0.44) EPHX2NR1H4CFDACLYSENP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333383-A1 N-OXIDE COMPOUNDS AND USE THEREOF SK BIOPHARMACEUTICALS CO., LTD. (KR) 2025-10-30 — — US claimed
EP-4514777-A1 N-OXIDE COMPOUNDS AND USE THEREOF SK Biopharmaceuticals Co., Ltd. (KR) 2025-03-05 — — EP claimed
WO-2023211195-A1 N-OXIDE COMPOUNDS AND USE THEREOF SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-11-02 — — WO claimed
US-20250333383-A1 N-OXIDE COMPOUNDS AND USE THEREOF SK BIOPHARMACEUTICALS CO., LTD. (KR) 2025-10-30 — — US disclosed
EP-4514777-A1 N-OXIDE COMPOUNDS AND USE THEREOF SK Biopharmaceuticals Co., Ltd. (KR) 2025-03-05 — — EP disclosed
WO-2023211195-A1 N-OXIDE COMPOUNDS AND USE THEREOF SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-11-02 — — WO disclosed
WO-2023211195-A1 N-OXIDE COMPOUNDS AND USE THEREOF SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-11-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333383-A1 N-OXIDE COMPOUNDS AND USE THEREOF SCNN1B, SCN1B, SCN2B EPHX2 1625/4885NR1H4 1118/4885SUCNR1 560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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