Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 13/20 | 0.43 |
| ▸ | GLP1R | P43220 | 1/20 | 0.42 |
| ▸ | WHR1 | P49842 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30681940 | 1.00 | SCN10A (0.43) | SCN10AGLP1RWHR1ALDH1A1MAPT | |
| SCHEMBL26617552 | 0.85 | MAPT (0.46) | SCN10AALDH1A1MAPTMAOB | |
| SCHEMBL30681915 | 0.85 | MAPT (0.46) | SCN10AALDH1A1MAPTMAOB | |
| SCHEMBL31345669 | 0.83 | SCN10A (0.44) | SCN10AGLP1R | |
| SCHEMBL26618095 | 0.83 | SCN10A (0.44) | SCN10AGLP1R | |
| SCHEMBL21905957 | 0.79 | SCN10A (0.57) | SCN10AALDH1A1 | |
| SCHEMBL26617871 | 0.76 | MAOB (0.45) | SCN10AMAOB | |
| SCHEMBL25391058 | 0.75 | SCN10A (0.60) | SCN10A | |
| SCHEMBL30681918 | 0.74 | FABP3 (0.44) | SCN10AMAOB | |
| SCHEMBL26617572 | 0.74 | SCN10A (0.44) | SCN10AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023211990-A1 | BICYCLIC HETEROCYCLIC AMIDE INHIBITORS OF NA V1.8 FOR THE TREATMENT OF PAIN | SITEONE THERAPEUTICS, INC. (US) | 2023-11-02 | — | — | WO | disclosed |