Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
| ▸ | SCN10A | Q9Y5Y9 | 16/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | AKT2 | P31751 | 1/20 | 0.40 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26617770 | 1.00 | FABP3 (0.44) | FABP3FABP4FABP5SCN10AMAOB | |
| SCHEMBL26617572 | 0.91 | SCN10A (0.44) | FABP3FABP4FABP5SCN10AMAOB | |
| SCHEMBL26617837 | 0.88 | SCN10A (0.40) | SCN10AMAOB | |
| SCHEMBL26617866 | 0.87 | RXFP1 (0.49) | SCN10A | |
| SCHEMBL31345669 | 0.86 | SCN10A (0.44) | SCN10A | |
| SCHEMBL26618095 | 0.86 | SCN10A (0.44) | SCN10A | |
| SCHEMBL26617769 | 0.85 | ALDH1A1 (0.46) | SCN10AMAOB | |
| SCHEMBL26618013 | 0.85 | SCN10A (0.44) | SCN10A | |
| SCHEMBL26617826 | 0.84 | MEN1 (0.48) | SCN10AMAOB | |
| SCHEMBL26617935 | 0.83 | SCN10A (0.39) | SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585247-A | Bicyclic heterocyclic amide inhibitors of nav1.8 for the treatment of pain | 赛特温治疗公司 | 2025-03-07 | — | — | CN | disclosed |
| EP-4514789-A1 | <SUP2/>? <SUB2/>?V?BICYCLIC HETEROCYCLIC AMIDE INHIBITORS OF NA1.8 FOR THE TREATMENT OF PAIN | SiteOne Therapeutics, Inc. (US) | 2025-03-05 | — | — | EP | disclosed |
| WO-2023211990-A1 | BICYCLIC HETEROCYCLIC AMIDE INHIBITORS OF NA V1.8 FOR THE TREATMENT OF PAIN | SITEONE THERAPEUTICS, INC. (US) | 2023-11-02 | — | — | WO | disclosed |