Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CALCRL | Q16602 | 13/20 | 0.37 |
| ▸ | CALCB | P10092 | 1/20 | 0.36 |
| ▸ | ADM2 | Q7Z4H4 | 1/20 | 0.36 |
| ▸ | CALCA | P06881 | 3/20 | 0.35 |
| ▸ | RAMP1 | O60894 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30637915 | 1.00 | KCNH2 (0.38) | KCNH2CALCRLCALCBADM2CALCA | |
| SCHEMBL26619185 | 0.92 | CALCRL (0.38) | KCNH2CALCRLCALCBADM2CALCA | |
| SCHEMBL30637920 | 0.92 | CALCRL (0.38) | KCNH2CALCRLCALCBADM2CALCA | |
| SCHEMBL26619068 | 0.85 | CALCRL (0.39) | CALCRLCALCBADM2CALCARAMP1 | |
| SCHEMBL30637910 | 0.85 | CALCRL (0.39) | CALCRLCALCBADM2CALCARAMP1 | |
| SCHEMBL31511804 | 0.84 | CALCA (0.36) | CALCRLCALCBADM2CALCARAMP1 | |
| SCHEMBL31511795 | 0.81 | CALCRL (0.38) | CALCRLCALCBADM2CALCARAMP1 | |
| SCHEMBL30637913 | 0.77 | ADM2 (0.45) | CALCRLCALCBADM2CALCARAMP1 | |
| SCHEMBL30637971 | 0.77 | ADM2 (0.45) | CALCRLCALCBADM2CALCARAMP1 | |
| SCHEMBL30637926 | 0.77 | ADM2 (0.45) | CALCRLCALCBADM2CALCARAMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003762-A | Piperidine formamide aza indane derivative, preparation method and application thereof | 熙源安健医药（上海）有限公司 | 2023-11-07 | — | — | CN | disclosed |
| WO-2023208124-A1 | PIPERIDINE CARBOXAMIDE AZAINDANE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF | 熙源安健医药（上海）有限公司 | 2023-11-02 | — | — | WO | disclosed |