Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.47 |
| ▸ | FLT3 | P36888 | 2/20 | 0.45 |
| ▸ | BTK | Q06187 | 2/20 | 0.45 |
| ▸ | SYK | P43405 | 4/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 4/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26619999 | 0.82 | BRD4 (0.50) | BRD4FLT3BTKSYKALK | |
| SCHEMBL26619844 | 0.81 | CCND3 (0.56) | BRD4FLT3BTKSYKALK | |
| SCHEMBL30515504 | 0.77 | SYK (0.48) | BRD4FLT3BTKSYKALK | |
| SCHEMBL26619900 | 0.76 | BRD4 (0.45) | BRD4FLT3BTKSYKALK | |
| SCHEMBL26619856 | 0.72 | CTSC (0.39) | BRD4ALK | |
| SCHEMBL26619927 | 0.72 | CHRM4 (0.38) | BRD4BTKSYK | |
| SCHEMBL16752980 | 0.70 | ALK (0.78) | ALK | |
| Hydrochloric Acid SCHEMBL17838914 | 0.69 | TNK2 (0.68) | ALKJAK2 | |
| SCHEMBL16752971 | 0.69 | ALK (0.55) | ALK | |
| SCHEMBL26619901 | 0.69 | MAPK10 (0.40) | BRD4ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213211-A9 | 2,4-DISUBSTITUTED-5-FLUOROPYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF | 长沙晶易医药科技股份有限公司 | 2024-03-21 | — | — | WO | disclosed |
| WO-2023213211-A1 | 2,4-DISUBSTITUTED-5-FLUOROPYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF | 长沙晶易医药科技股份有限公司 | 2023-11-09 | — | — | WO | disclosed |