Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | EP300 | Q09472 | 2/20 | 0.36 |
| ▸ | MYC | P01106 | 2/20 | 0.36 |
| ▸ | MAX | P61244 | 2/20 | 0.36 |
| ▸ | OGA | O60502 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 1/20 | 0.35 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1343187 | 0.96 | LPAR1 (0.39) | ALDH1A1TSHRLPAR1EP300MYC | |
| SCHEMBL1342497 | 0.95 | ITGB1 (0.42) | ITGB1ITGA4ALDH1A1TSHRLPAR1 | |
| SCHEMBL1343247 | 0.86 | ITGB1 (0.37) | ITGB1ITGA4ALDH1A1TSHRLPAR1 | |
| SCHEMBL1342668 | 0.86 | LPAR1 (0.39) | ALDH1A1TSHRLPAR1MYCMAX | |
| SCHEMBL1343714 | 0.85 | LPAR1 (0.38) | LPAR1EP300MYCMAXMEN1 | |
| SCHEMBL1342817 | 0.85 | ADRB2 (0.40) | ITGB1ITGA4LPAR1MYCMAX | |
| SCHEMBL1340678 | 0.84 | ITGB1 (0.41) | ITGB1ITGA4ALDH1A1LPAR1MYC | |
| SCHEMBL6695295 | 0.84 | AURKA (0.40) | LPAR1MAPK14MAPK13CDK2 | |
| SCHEMBL1343242 | 0.84 | LPAR1 (0.37) | LPAR1EP300MYCMAXMEN1 | |
| SCHEMBL1342849 | 0.83 | LPAR1 (0.39) | ALDH1A1LPAR1MYCMAXMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |