Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.56 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.56 |
| ▸ | BRD4 | O60885 | 3/20 | 0.56 |
| ▸ | SYK | P43405 | 6/20 | 0.55 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 2/20 | 0.52 |
| ▸ | BTK | Q06187 | 2/20 | 0.52 |
| ▸ | STAT6 | P42226 | 1/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.51 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | GSK3A | P49840 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.51 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26619897 | 0.84 | BRD4 (0.55) | BRD4SYKEGFRFLT3BTK | |
| SCHEMBL30670378 | 0.83 | AURKA (0.64) | BRD4SYKEGFRFLT3BTK | |
| SCHEMBL26619859 | 0.83 | BRD4 (0.59) | BRD4SYKSTK17AEGFRFLT3 | |
| SCHEMBL12277771 | 0.76 | BRD4 (0.80) | PDGFRBPDGFRABRD4STK17AEGFR | |
| SCHEMBL30515505 | 0.74 | SYK (0.57) | PDGFRBPDGFRABRD4SYKSTK17A | |
| SCHEMBL655104 | 0.73 | GSK3A (0.62) | SYKSTK17AEGFRFLT3BTK | |
| SCHEMBL28705131 | 0.73 | SYK (0.61) | BRD4SYKEGFRFLT3BTK | |
| SCHEMBL29389394 | 0.73 | SYK (0.61) | BRD4SYKEGFRFLT3BTK | |
| SCHEMBL24507655 | 0.73 | TGFBR1 (0.66) | PDGFRBPDGFRABRD4SYKSTK17A | |
| SCHEMBL4383043 | 0.72 | ALK (0.60) | SYKALKPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213211-A9 | 2,4-DISUBSTITUTED-5-FLUOROPYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF | 长沙晶易医药科技股份有限公司 | 2024-03-21 | — | — | WO | claimed |
| WO-2023213211-A1 | 2,4-DISUBSTITUTED-5-FLUOROPYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF | 长沙晶易医药科技股份有限公司 | 2023-11-09 | — | — | WO | claimed |