Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1991834 | 0.75 | CDK2 (0.53) | CDK2KDM4EALDH1A1KDM4DPOLB | |
| SCHEMBL9728946 | 0.75 | CDK2 (0.53) | CDK2KDM4EALDH1A1KDM4DPOLB | |
| SCHEMBL14033080 | 0.72 | KDM4E (0.40) | KDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL15333599 | 0.72 | LPL (0.32) | TGFBR1 | |
| SCHEMBL25209931 | 0.72 | CDK2 (0.46) | CDK2KDM4EALDH1A1KDM4DPOLB | |
| SCHEMBL14820098 | 0.71 | CDK2 (0.49) | CDK2KDM4EALDH1A1KDM4DPOLB | |
| SCHEMBL25097590 | 0.71 | KDM4E (0.51) | CDK2KDM4EALDH1A1KDM4DPOLB | |
| SCHEMBL26622039 | 0.71 | ATR (0.32) | — | |
| SCHEMBL12613502 | 0.70 | KDR (0.55) | CDK2KDM4EALDH1A1KDM4DHTT | |
| SCHEMBL14805722 | 0.68 | CDK2 (0.45) | CDK2KDM4EALDH1A1KDM4DPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023214325-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES AND USES THEREOF AS TET2 INHIBITORS | NOVARTIS AG (CH) | 2023-11-09 | — | — | WO | disclosed |