Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30640478 | 1.00 | KDM4E (0.54) | KDM4EALDH1A1POLBRXFP1LMNA | |
| SCHEMBL26621945 | 0.80 | KDM4E (0.57) | KDM4EALDH1A1POLBRXFP1LMNA | |
| SCHEMBL4171150 | 0.75 | KDR (0.66) | ALDH1A1RXFP1LMNAKDRNPC1 | |
| SCHEMBL26621884 | 0.75 | NPC1 (0.43) | KDM4EALDH1A1RXFP1KDRNPC1 | |
| SCHEMBL30640470 | 0.75 | NPC1 (0.43) | KDM4EALDH1A1RXFP1KDRNPC1 | |
| SCHEMBL30640466 | 0.74 | KDM4E (0.51) | KDM4EALDH1A1POLBRXFP1LMNA | |
| SCHEMBL26622008 | 0.74 | KDM4E (0.51) | KDM4EALDH1A1POLBRXFP1LMNA | |
| SCHEMBL4168101 | 0.71 | LCK (0.64) | KDRABL1NPC1RAB9AMEN1 | |
| SCHEMBL4160576 | 0.70 | KDR (0.52) | ALDH1A1RXFP1LMNAKDRNPC1 | |
| SCHEMBL26621968 | 0.70 | KDM4E (0.49) | KDM4EALDH1A1POLBRXFP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023214325-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES AND USES THEREOF AS TET2 INHIBITORS | NOVARTIS AG (CH) | 2023-11-09 | — | — | WO | disclosed |