Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | TPMT | P51580 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20929758 | 0.86 | KMT2A (0.58) | MAPTKMT2ATSHRCYP3A4CYP1A2 | |
| SCHEMBL26743870 | 0.85 | TSHR (0.67) | MAPTKMT2ATSHRCYP3A4CYP1A2 | |
| SCHEMBL28872919 | 0.84 | KMT2A (0.58) | MAPTKMT2ACYP3A4CYP1A2KDM4E | |
| SCHEMBL20105049 | 0.83 | MAPT (0.56) | MAPTKMT2ATSHRCYP3A4CYP1A2 | |
| SCHEMBL9904971 | 0.82 | KMT2A (0.54) | MAPTKMT2ATSHRCYP3A4KDM4E | |
| SCHEMBL18808078 | 0.81 | TSHR (0.45) | MAPTKMT2ATSHRCYP3A4CYP1A2 | |
| SCHEMBL27660178 | 0.81 | TSHR (0.50) | MAPTKMT2ATSHRCYP3A4CYP1A2 | |
| SCHEMBL14451131 | 0.80 | KMT2A (0.58) | MAPTKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15858608 | 0.79 | KMT2A (0.57) | MAPTKMT2ACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL25311659 | 0.78 | PKM (0.53) | MAPTKMT2ACYP3A4CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215742-A2 | ENZYMATIC REDUCTION OR REDUCTIVE AMINATION OF ARYL AND HETEROCYCLIC CARBOXYLIC ACIDS AND ALDEHYDES | KUNJAPUR ADITYA (US) | 2023-11-09 | — | — | WO | disclosed |