Known targets — ChEMBL curated mechanism
ADRB1ADRB2ATP4AATP4BAXLCHRM2CHRM3DRD2FLT3HRH1HTR2AHTR2BHTR2CKCNH2KMT2AMAP2K1MAP2K2MEN1MLNRPLK4RENS1PR1SLC6A2SLC6A4atpAatpBatpCatpDatpEatpFatpFHatpGpol
The experimentally established mechanism targets of Adenosine Phosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.87 |
| ▸ | KCNH2 known ✓ | Q12809 | 1/20 | 0.87 |
| ▸ | P2RY1 | P47900 | 5/20 | 0.87 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.87 |
| ▸ | SRC | P12931 | 2/20 | 0.87 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.87 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.87 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.87 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.87 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.87 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.87 |
| ▸ | LDHA | P00338 | 1/20 | 0.87 |
| ▸ | FBP1 | P09467 | 1/20 | 0.87 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.87 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.87 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.87 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.87 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.87 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.87 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.87 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenosine Phosphate SCHEMBL369697 | 0.94 | P2RY1 (0.85) | P2RY1P2RY2SRCSMN1; SMN2TRPM2 | |
| Adenosine Phosphate SCHEMBL790420 | 0.93 | P2RY1 (0.92) | P2RY1P2RY2SRCSMN1; SMN2TRPM2 | |
| Adenosine Phosphate SCHEMBL11977309 | 0.93 | P2RY1 (1.00) | P2RY1P2RY2SRCSMN1; SMN2TRPM2 | |
| Vidarabine Phosphate SCHEMBL144996 | 0.93 | P2RY1 (1.00) | P2RY1P2RY2SRCSMN1; SMN2TRPM2 | |
| Adenosine Phosphate SCHEMBL1338615 | 0.93 | P2RY1 (1.00) | P2RY1P2RY2SRCSMN1; SMN2TRPM2 | |
| Adenosine Phosphate SCHEMBL20277555 | 0.93 | P2RY1 (1.00) | P2RY1P2RY2SRCSMN1; SMN2TRPM2 | |
| Adenosine Phosphate SCHEMBL18785114 | 0.93 | P2RY1 (1.00) | P2RY1P2RY2SRCSMN1; SMN2TRPM2 | |
| Adenosine Phosphate SCHEMBL15646670 | 0.93 | P2RY1 (1.00) | P2RY1P2RY2SRCSMN1; SMN2TRPM2 | |
| Adenosine Phosphate SCHEMBL5588 | 0.93 | P2RY1 (1.00) | P2RY1P2RY2SRCSMN1; SMN2TRPM2 | |
| Adenosine Phosphate SCHEMBL13374692 | 0.93 | P2RY1 (1.00) | P2RY1P2RY2SRCSMN1; SMN2TRPM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213310-A1 | CARBON CHAIN SUBSTANCE FOR REGULATING TRANSMEMBRANE TRANSPORT AND FLUIDITY OF CELL MEMBRANES, AND PREPARATION AND USE THEREOF | 太阳雨林(北京)生物医药有限公司 | 2023-11-09 | — | — | WO | disclosed |
| CN-110507625-A | A kind of novel tenofovir disoproxil fumarate piece and preparation method thereof | SUZHOU DAWNRAYS PHARMACEUTICAL CO LTD | 2019-11-29 | — | — | CN | disclosed |
| CN-109900819-A | A kind of method that UPLC/MS-MS combination detects tenofovir in human serum | 南京海纳医药科技股份有限公司 | 2019-06-18 | — | — | CN | disclosed |