Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 17/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2907835 | 0.81 | GCGR (0.71) | GCGR | |
| SCHEMBL2649597 | 0.80 | GCGR (0.43) | GCGR | |
| SCHEMBL2648318 | 0.80 | GCGR (0.66) | GCGR | |
| SCHEMBL2647208 | 0.77 | GCGR (0.85) | GCGR | |
| SCHEMBL2653781 | 0.76 | GCGR (0.61) | GCGR | |
| SCHEMBL2648377 | 0.73 | GCGR (0.73) | GCGR | |
| SCHEMBL2647607 | 0.70 | GCGR (0.86) | GCGR | |
| SCHEMBL19126702 | 0.69 | GAA (0.38) | PTGS1PTGS2 | |
| SCHEMBL8496147 | 0.69 | GCGR (0.47) | GCGR | |
| SCHEMBL2647901 | 0.68 | GCGR (0.80) | GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934274-A1 | SUBSTITUTED PYRIDINES AND BIPHENYLS AS ANTI-HYPERCHOLESTERINEMIC, ANTI-HYPERLIPOPROTEINEMIC AND ANTI-HYPERGLYCEMIC AGENTS | Bayer Corporation (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998004528-A2 | SUBSTITUTED PYRIDINES AND BIPHENYLS AS ANTI-HYPERCHOLESTERINEMIC, ANTI-HYPERLIPOPROTEINEMIC AND ANTI-HYPERGLYCEMIC AGENTS | BAYER CORPORATION (US) | 1998-02-05 | — | — | WO | disclosed |