Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 8/20 | 0.47 |
| ▸ | USP7 | Q93009 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 7/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8492678 | 0.77 | LTB4R (0.45) | LTB4RLTB4R2 | |
| SCHEMBL11881502 | 0.69 | NPC1 (0.43) | KDM4EMAPK1HTT | |
| SCHEMBL9744064 | 0.69 | NPC1 (0.48) | GCGRLMNAMAPTXBP1HIF1A | |
| SCHEMBL2662506 | 0.69 | GCGR (0.51) | GCGR | |
| SCHEMBL4386879 | 0.69 | CNR2 (0.42) | LTB4RLTB4R2TP53 | |
| SCHEMBL919514 | 0.68 | PPARG (0.53) | — | |
| SCHEMBL6469970 | 0.68 | PPARG (0.53) | — | |
| SCHEMBL5208612 | 0.67 | ALOX5 (0.57) | GCGRLMNAMAPTXBP1HIF1A | |
| SCHEMBL2648377 | 0.67 | GCGR (0.73) | GCGR | |
| SCHEMBL4387388 | 0.67 | ESR1 (0.44) | GCGRUSP7KDM4EHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914340-A | ADMINISTERING TO TREAT OR INHIBIT SKIN DISORDERS SUCH AS ATOPIC DERMATITIS, CONTACT DERMATITIS, BULLOUS PEMPHIGOID, URTICARIA DISEASES, PETYRIASIS RUBRA PILARIS AND DYSHEDROSIS | ELI LILLY AND COMPANY (US) | 1999-06-22 | — | — | US | claimed |
| US-5910505-A | Leukotriene antagonists for use in the treatment or inhibition of oral squamous cell carcinoma | ELI LILLY AND COMPANY (US) | 1999-06-08 | — | — | US | claimed |
| US-5817684-A | ADMINISTERING AN AROMATIC ALCOHOL COMPOUND | ELI LILLY AND COMPANY (US) | 1998-10-06 | — | — | US | claimed |
| US-5914340-A | ADMINISTERING TO TREAT OR INHIBIT SKIN DISORDERS SUCH AS ATOPIC DERMATITIS, CONTACT DERMATITIS, BULLOUS PEMPHIGOID, URTICARIA DISEASES, PETYRIASIS RUBRA PILARIS AND DYSHEDROSIS | ELI LILLY AND COMPANY (US) | 1999-06-22 | — | — | US | disclosed |
| US-5910505-A | Leukotriene antagonists for use in the treatment or inhibition of oral squamous cell carcinoma | ELI LILLY AND COMPANY (US) | 1999-06-08 | — | — | US | disclosed |
| US-5817684-A | ADMINISTERING AN AROMATIC ALCOHOL COMPOUND | ELI LILLY AND COMPANY (US) | 1998-10-06 | — | — | US | disclosed |