Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 19/20 | 0.62 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.61 |
| ▸ | TUBB | P07437 | 1/20 | 0.61 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.61 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.61 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.61 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.61 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.61 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.61 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.61 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.61 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.61 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.61 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.61 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.61 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16346487 | 0.92 | TUBB4A (0.70) | ESR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16346111 | 0.88 | ESR1 (0.81) | ESR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16346490 | 0.88 | ESR1 (0.62) | ESR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16346286 | 0.88 | ESR1 (0.63) | ESR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14613446 | 0.87 | ESR1 (0.76) | ESR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7106407 | 0.85 | ESR1 (0.62) | ESR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7102538 | 0.84 | ESR1 (0.57) | ESR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL26625400 | 0.83 | TUBB4A (0.54) | ESR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30619799 | 0.83 | TUBB4A (0.54) | ESR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7936791 | 0.82 | PRNP (0.55) | ESR1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023212599-A2 | COMPOUNDS AND METHODS FOR TARGETED DEGRADATION OF ESTROGEN RECEPTORS | ENDOTARGET INC. (US) | 2023-11-02 | — | — | WO | disclosed |