Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.71 |
| ▸ | ACHE | P22303 | 3/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MPL | P40238 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28866158 | 0.89 | HTR2B (0.61) | HTR2BACHECYP2C9SCN9ACYP2C19 | |
| SCHEMBL2554961 | 0.85 | PIM1 (0.62) | HTR2BACHECYP2C9SCN9ACYP2C19 | |
| SCHEMBL2693403 | 0.85 | ACHE (0.63) | HTR2BACHEHDAC1HDAC8HDAC6 | |
| Pulicatins F SCHEMBL12469099 | 0.83 | HTR2B (1.00) | HTR2BACHECYP2C9SCN9ACYP2C19 | |
| SCHEMBL28183740 | 0.83 | HTR2B (0.54) | HTR2BACHECYP2C9SCN9ACYP2C19 | |
| SCHEMBL28216860 | 0.82 | HTR2B (0.69) | HTR2BACHECYP2C9SCN9ACYP2C19 | |
| SCHEMBL31351218 | 0.81 | HTR2B (0.60) | HTR2BACHECYP2C9SCN9ACYP2C19 | |
| Ammonia Solution, Strong SCHEMBL27976670 | 0.81 | HTR2B (0.68) | HTR2BACHECYP2C9SCN9ACYP2C19 | |
| SCHEMBL14463683 | 0.80 | HTR2B (0.66) | HTR2BACHECYP2C9SCN9ACYP2C19 | |
| SCHEMBL27976668 | 0.80 | HTR2B (0.66) | HTR2BACHECYP2C9SCN9ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104640858-B | Cyclic ether pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use | 霍夫曼-拉罗奇有限公司 | 2018-11-06 | — | — | CN | claimed |
| CN-103987707-B | The base heterocyclic radical benzamide compound of pyrazoles 4 and application method | 霍夫曼-拉罗奇有限公司 | 2017-11-07 | — | — | CN | claimed |
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |
| WO-2024082724-A1 | PIM KINASE INHIBITOR IN COMBINATION WITH KRAS INHIBITOR | NINGBO NEWBAY TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2024-04-25 | — | — | WO | disclosed |
| WO-2023202563-A1 | AKT INHIBITOR IN COMBINATION WITH PIM KINASE INHIBITOR | NEWBAY TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2023-10-26 | — | — | WO | disclosed |
| CN-102625807-A | 4-substituted pyridin-3-yl-carboxamide compounds and methods of use | HOFFMANN LA ROCHE | 2012-08-01 | — | — | CN | disclosed |