Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5726133 | 1.00 | MAPK14 (0.60) | MAPK14 | |
| SCHEMBL22589253 | 0.91 | MAPK14 (0.48) | MAPK14 | |
| SCHEMBL22589139 | 0.90 | MAPK14 (0.48) | MAPK14 | |
| SCHEMBL6950656 | 0.86 | CYP2D6 (0.45) | — | |
| SCHEMBL6952425 | 0.85 | TRPC3 (0.48) | — | |
| SCHEMBL3099127 | 0.84 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL1376871 | 0.81 | MAPK14 (0.69) | MAPK14 | |
| SCHEMBL5725265 | 0.81 | MAPK14 (0.74) | MAPK14 | |
| SCHEMBL22589298 | 0.80 | TRPC3 (0.51) | MAPK14 | |
| SCHEMBL22589274 | 0.80 | TRPC3 (0.51) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776954-A | GLUCAGON ANTAGONISTS | MERCK & CO., INC. (US) | 1998-07-07 | — | — | US | disclosed |
| WO-1997016442-A1 | SUBSTITUTED PYRIDYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO., INC. (US) | 1997-05-09 | — | — | WO | disclosed |