Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 15/20 | 0.73 |
| ▸ | MAPK14 | Q16539 | 13/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2662945 | 0.84 | GCGR (1.00) | GCGRMAPK14KDM4EALDH1A1CYP3A4 | |
| SCHEMBL2662944 | 0.81 | GCGR (0.60) | GCGRMAPK14 | |
| SCHEMBL2646773 | 0.80 | GCGR (1.00) | GCGRMAPK14 | |
| SCHEMBL28643906 | 0.78 | GCGR (0.68) | GCGRMAPK14KDM4EALDH1A1CYP3A4 | |
| SCHEMBL29691553 | 0.76 | GCGR (1.00) | GCGRMAPK14KDM4EALDH1A1CYP3A4 | |
| SCHEMBL6362882 | 0.76 | GCGR (1.00) | GCGRMAPK14KDM4EALDH1A1CYP3A4 | |
| SCHEMBL2645507 | 0.75 | GCGR (0.88) | GCGRMAPK14 | |
| SCHEMBL2662940 | 0.74 | GCGR (0.97) | GCGRMAPK14 | |
| SCHEMBL8857820 | 0.72 | ALOX5AP (0.46) | GCGRMAPK14ALDH1A1MAPTHPGD | |
| SCHEMBL2658421 | 0.72 | IMPDH2 (0.49) | GCGRMAPK14CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997016442-A1 | SUBSTITUTED PYRIDYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO., INC. (US) | 1997-05-09 | — | — | WO | disclosed |