Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30309711 | 0.85 | CYP2C19 (0.42) | BRD4IDO1TDO2MAPTLMNA | |
| SCHEMBL20505810 | 0.83 | MAPT (0.43) | BRD4IDO1TDO2MAPTLMNA | |
| SCHEMBL29571912 | 0.83 | MAPT (0.43) | BRD4IDO1TDO2MAPTLMNA | |
| SCHEMBL29651347 | 0.78 | BRD4 (0.37) | BRD4MAPTLMNANPSR1HTT | |
| SCHEMBL20506223 | 0.78 | BRD4 (0.37) | BRD4MAPTLMNANPSR1HTT | |
| SCHEMBL22864673 | 0.76 | BRD4 (0.37) | BRD4IDO1TDO2MAPTLMNA | |
| SCHEMBL31378040 | 0.76 | BRD4 (0.37) | BRD4IDO1TDO2MAPTLMNA | |
| SCHEMBL29571607 | 0.76 | BRD4 (0.35) | BRD4MAPTLMNANPSR1HTT | |
| SCHEMBL20573837 | 0.76 | BRD4 (0.35) | BRD4MAPTLMNANPSR1HTT | |
| SCHEMBL18381344 | 0.75 | BRD4 (0.36) | BRD4IDO1TDO2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339896-A1 | HPK1 INHIBITORS AND USES THEREOF | REGOR PHARMACEUTICALS, INC. | 2023-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339896-A1 | HPK1 INHIBITORS AND USES THEREOF | HIPK1, MAPKAPK5, MLKL | BRD4 3072/4885IDO1 3823/4885TDO2 4460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.