Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | FOLR1 | P15328 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12313820 | 0.84 | RAB9A (0.56) | KMT2AL3MBTL1LMNARXFP1GAA | |
| SCHEMBL2650949 | 0.80 | GAA (0.41) | KMT2ALMNARXFP1GAANPSR1 | |
| SCHEMBL277890 | 0.79 | KMT2A (0.55) | KMT2AL3MBTL1LMNARXFP1GAA | |
| SCHEMBL5630030 | 0.78 | MAPK1 (0.63) | KMT2ALMNARXFP1GAANPSR1 | |
| SCHEMBL279950 | 0.78 | KMT2A (0.71) | KMT2AL3MBTL1LMNARXFP1GAA | |
| SCHEMBL2663028 | 0.77 | NPC1 (0.49) | KMT2AL3MBTL1LMNARAB9ANPC1 | |
| SCHEMBL14395888 | 0.75 | KMT2A (0.51) | KMT2AL3MBTL1LMNARXFP1GAA | |
| SCHEMBL8791196 | 0.74 | HPGD (0.46) | KMT2ARXFP1GAANPSR1KDM4E | |
| SCHEMBL12265882 | 0.74 | KMT2A (0.60) | KMT2AL3MBTL1LMNARXFP1GAA | |
| SCHEMBL4028375 | 0.74 | DAO (0.54) | KMT2ALMNARXFP1ALDH1A1PRNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000069810-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-11-23 | — | — | WO | disclosed |