SCHEMBL26631287

SCHEMBL26631287

CC(=O)Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1OCOCCNC(=O)C(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ SLC29A1 Q99808 2/20 0.50
▸ MEN1 O00255 1/20 0.48
▸ KMT2A Q03164 1/20 0.48
▸ ADORA2A P29274 1/20 0.45
▸ ADORA2B P29275 1/20 0.45
▸ PRMT5 O14744 1/20 0.45
▸ WDR77 Q9BQA1 1/20 0.45
▸ ADORA1 P30542 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26631283 1.00 SLC29A1 (0.50) SLC29A1MEN1KMT2AADORA2AADORA2B
SCHEMBL19509820 0.88 ADORA1 (0.50) SLC29A1ADORA2AADORA2BADORA1
SCHEMBL21652362 0.88 ADORA1 (0.50) SLC29A1ADORA2AADORA2BADORA1
SCHEMBL19500431 0.88 ADORA1 (0.50) SLC29A1ADORA2AADORA2BADORA1
SCHEMBL19981006 0.84 SLC29A1 (0.51) SLC29A1MEN1KMT2AADORA2AADORA2B
SCHEMBL14727515 0.84 SLC29A1 (0.51) SLC29A1MEN1KMT2AADORA2AADORA2B
SCHEMBL20215742 0.84 SLC29A1 (0.51) SLC29A1MEN1KMT2AADORA2AADORA2B
SCHEMBL15850629 0.84 SLC29A1 (0.51) SLC29A1MEN1KMT2AADORA2AADORA2B
SCHEMBL26631290 0.84 TYMP (0.50) ADORA2AADORA2BADORA1
SCHEMBL26631288 0.84 TYMP (0.50) ADORA2AADORA2BADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357767-A1 NOVEL NUCLEIC ACID MOLECULE INHIBITING EXPRESSION OF TARGET GENE BONAC CORPORATION (JP) 2023-11-09 — — US disclosed
EP-4206325-A1 NOVEL NUCLEIC ACID MOLECULE INHIBITING EXPRESSION OF TARGET GENE BONAC CORPORATION (JP) 2023-07-05 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357767-A1 NOVEL NUCLEIC ACID MOLECULE INHIBITING EXPRESSION OF TARGET GENE SNRPE, DDX21, DCLRE1B SLC29A1 704/4885MEN1 3615/4885KMT2A 1649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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