DCLRE1B — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL10397478	0.72	3/20
SCHEMBL11296003	0.70	3/20
SCHEMBL7019419	0.66	3/20
SCHEMBL13681701	0.66	3/20
Hydrochloric Acid (SCHEMBL5704000)	0.62	3/20
Benzene (SCHEMBL1931924)	0.61	3/20
SCHEMBL2356669	0.61	3/20
SCHEMBL2770912	0.59	3/20
SCHEMBL8887303	0.58	3/20
SCHEMBL2251799	0.57	3/20
SCHEMBL8889501	0.57	3/20
SCHEMBL1931921	0.56	3/20
SCHEMBL2254822	0.56	3/20
SCHEMBL9518777	0.55	3/20
SCHEMBL6283584	0.54	3/20
SCHEMBL4953918	0.52	3/20
SCHEMBL6256752	0.52	3/20
SCHEMBL1099041	0.52	3/20
SCHEMBL8999909	0.52	3/20
SCHEMBL3174141	0.51	3/20

Clinical trials — most relevant to DCLRE1B by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Mobilization and Collection of Peripheral Blood Stem Cells in Patients With Fanconi Anemia Using G-CSF and AMD3100	PHASE1/PHASE2	COMPLETED
Clinical Study of EBV-LMP1 Targeted DNAzyme to Treat Nasopharyngeal Carcinoma	PHASE1/PHASE2	COMPLETED
Chlorambucil in Metastatic PDAC Patients Bearing a Germ Line DNA Defects Repair Mutations (SALE Trial)	PHASE2	UNKNOWN
A Phase I Trial of SHR3162 in Subjects With Advanced Solid Tumors	PHASE1	COMPLETED
A Proof of Concept Study for the DNA Repair Driven by the Mesenchymal Stem Cells in Critical COVID-19 Patients	nan	COMPLETED
PCD New Gene Discovery	nan	COMPLETED
DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study	nan	RECRUITING
Genetics of Primary Ciliary Dyskinesia	nan	COMPLETED
Germline Alterations of Tumor Susceptibility Genes in New York Cancer Patients	nan	ACTIVE_NOT_RECRUITING
DNA Repair Genes and Outcomes in Patients With Stage III NSCLC	nan	UNKNOWN
DNA Damage & Repair Proteins In Patients With Atherosclerotic Coronary Artery Disease	nan	COMPLETED
Telomere Repair Gene Mutation in Inflammatory Bowel Disease	nan	COMPLETED
Study of the Effect of Innate on the Inflammatory Response to Endotoxin	nan	RECRUITING
A Dose-escalation Trial of Stereotactic Ablative Body Radiotherapy for Non-spine Bone & Lymph Node Oligometastates	nan	COMPLETED
Telomeres Length in Israeli Fibrotic ILD Patients	nan	ENROLLING_BY_INVITATION
Hereditary Nonpolyposis Colorectal Cancer in Taiwan-Related Genetic Study and Clinical Applications	nan	UNKNOWN
Investigation of Copy Number Variations and Genetic Variants in POI	nan	RECRUITING
Predictive Study of Radiation Induced Sarcoma	nan	COMPLETED
Molecular Genetics Study of Nasopharyngeal Carcinoma: Characterization of NCP Susceptibility Gene(s)	nan	COMPLETED
ADAR1 Expression Level in Rectal Cancer	nan	RECRUITING
Study of Markers of Cosmic Radiation Exposure and Effect Among Flight Crews	nan	COMPLETED
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve	nan	UNKNOWN
Positional Cloning of the Gene(s) Responsible for Alagille Syndrome	nan	COMPLETED
Thoracic Aortic Dilatation Syndromes	nan	COMPLETED
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic	nan	COMPLETED
Novel Biomarkers in the Neoplastic Progression of Barrett's Esophagus	nan	ACTIVE_NOT_RECRUITING
Immunogenetics of Visceral Leishmaniasis	nan	COMPLETED
Molecular Genetic Studies of Childhood Brain Tumors and Blood Samples	nan	COMPLETED
Prospective Genetic Study in Patients With Ovarian Insufficiency	nan	UNKNOWN
Genes That Affect Disease Outcome in Patients With Metastatic Colorectal Cancer	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a DCLRE1B binder may also engage these)

Protein	Name	Similarity
D2H8V8	—	1.000	D2H8V8 →
Q8C7W7	—	0.995	Q8C7W7 →
Q4KLY6	—	0.995	Q4KLY6 →
Q5QJC3	—	0.990	Q5QJC3 →
Q5XIX3	—	0.984	Q5XIX3 →
Q8K4J0	—	0.983	Q8K4J0 →
A0JPN4	—	0.978	A0JPN4 →
Q400G9	—	0.977	Q400G9 →
Q96AY2	—	0.976	Q96AY2 →
Q8C5V5	—	0.976	Q8C5V5 →
Q5QJC2	—	0.975	Q5QJC2 →
Q5R6Z9	—	0.975	Q5R6Z9 →
Q400C9	—	0.975	Q400C9 →
Q5T7W7	—	0.975	Q5T7W7 →
B0V2S2	—	0.975	B0V2S2 →
D2HNY3	—	0.974	D2HNY3 →
Q91XS1	—	0.974	Q91XS1 →
Q5RF77	—	0.974	Q5RF77 →
Q69ZT1	—	0.974	Q69ZT1 →
Q5RGE5	—	0.974	Q5RGE5 →
Q96SD1	—	0.973	Q96SD1 →
Q60953	—	0.973	Q60953 →
A4QNA8	—	0.973	A4QNA8 →
Q6ZW76	—	0.973	Q6ZW76 →
Q3U5Q7	—	0.973	Q3U5Q7 →
Q64LD2	—	0.973	Q64LD2 →
Q68DX3	—	0.973	Q68DX3 →
Q8R2S1	—	0.973	Q8R2S1 →
O43304	—	0.973	O43304 →
P0C218	—	0.973	P0C218 →