Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26632110 | 0.90 | PIM2 (0.33) | AURKAPDPK1AURKBCHRM4 | |
| SCHEMBL26632142 | 0.87 | USP30 (0.32) | CHRM4 | |
| SCHEMBL26632148 | 0.87 | CHRM4 (0.33) | AURKAPDPK1AURKBCHRM4 | |
| SCHEMBL26758703 | 0.85 | AURKA (0.46) | AURKAPDPK1AURKB | |
| SCHEMBL30628535 | 0.85 | AURKA (0.46) | AURKAPDPK1AURKB | |
| SCHEMBL26632113 | 0.83 | ALDH1A1 (0.36) | — | |
| SCHEMBL16694846 | 0.79 | CYP3A4 (0.39) | SMYD3 | |
| SCHEMBL13736950 | 0.79 | PIM2 (0.41) | CHRM4 | |
| SCHEMBL1710543 | 0.79 | PIM2 (0.41) | CHRM4 | |
| SCHEMBL15808618 | 0.79 | PIM2 (0.41) | CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023211256-A1 | NOVEL PIM KINASE INHIBITORS AND USES THEREOF | 제일약품주식회사 | 2023-11-02 | — | — | WO | disclosed |