Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2652263 | 0.85 | HDAC1 (0.46) | HDAC1CXCR4SMN1; SMN2 | |
| SCHEMBL9072674 | 0.84 | HDAC1 (0.57) | HDAC1CXCR4HRH3SMN1; SMN2GCGR | |
| SCHEMBL2651717 | 0.79 | GCGR (0.61) | HDAC1HRH3GCGR | |
| SCHEMBL2663270 | 0.78 | HRH3 (0.50) | HDAC1CXCR4HRH3GCGRCA1 | |
| SCHEMBL2650729 | 0.77 | GCGR (0.54) | HDAC1CXCR4HRH3ITGB3ITGA2B | |
| SCHEMBL2652054 | 0.77 | NPC1 (0.52) | HDAC1HRH3SMN1; SMN2CA1CA2 | |
| SCHEMBL9072917 | 0.76 | GCGR (0.56) | HDAC1CXCR4HRH3SMN1; SMN2GCGR | |
| SCHEMBL2663087 | 0.75 | HRH3 (0.47) | HDAC1CXCR4HRH3ITGB3ITGA2B | |
| SCHEMBL2663474 | 0.74 | GCGR (0.53) | HDAC1CXCR4HRH3GCGR | |
| SCHEMBL4087875 | 0.73 | GCGR (0.42) | CXCR4GCGRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000069810-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-11-23 | — | — | WO | disclosed |