Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 7/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GIPR | P48546 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2650729 | 0.86 | GCGR (0.54) | HRH3HDAC1CXCR4GCGRHDAC3 | |
| SCHEMBL2651717 | 0.81 | GCGR (0.61) | HRH3HDAC1GCGREPHX2NR1H4 | |
| SCHEMBL9072674 | 0.79 | HDAC1 (0.57) | HRH3HDAC1CXCR4GCGRCA1 | |
| SCHEMBL2663270 | 0.78 | HRH3 (0.50) | HRH3HDAC1CXCR4GCGRCA1 | |
| SCHEMBL2663474 | 0.76 | GCGR (0.53) | HRH3HDAC1CXCR4GCGREPHX2 | |
| SCHEMBL9072855 | 0.76 | GCGR (0.49) | HRH3GCGREPHX2NR1H4GIPR | |
| SCHEMBL9072917 | 0.76 | GCGR (0.56) | HRH3HDAC1CXCR4GCGREPHX2 | |
| SCHEMBL2663237 | 0.75 | HDAC1 (0.52) | HRH3HDAC1CXCR4GCGRCA1 | |
| SCHEMBL9072937 | 0.73 | CA1 (0.52) | HRH3HDAC1GCGRHDAC3CA1 | |
| SCHEMBL2663268 | 0.73 | HRH3 (0.48) | HRH3HDAC1CXCR4GCGRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000069810-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-11-23 | — | — | WO | disclosed |