SCHEMBL26632523

SCHEMBL26632523

C=Cc1cc(C(=O)OCC)cnc1CC.CCOC(=O)c1cnc(CC)c(C=O)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
ALDH1A1 P00352 3/20 0.39
LMNA P02545 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CA12 O43570 3/20 0.38
CA1 P00915 3/20 0.38
CA2 P00918 3/20 0.38
CA7 P43166 3/20 0.38
CA9 Q16790 3/20 0.38
CA14 Q9ULX7 3/20 0.38
MAOB P27338 2/20 0.37
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
DPP4 P27487 2/20 0.35
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
KDM4E B2RXH2 1/20 0.34
HSP90AA1 P07900 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31405437 0.95 CYP2C9 (0.47) CYP2C9CYP2C19ALDH1A1LMNACA12
SCHEMBL31405429 0.93 CYP2C9 (0.48) CYP2C9CYP2C19ALDH1A1LMNASMN1; SMN2
SCHEMBL26632464 0.85 CYP2C9 (0.41) CYP2C9CYP2C19ALDH1A1LMNASMN1; SMN2
SCHEMBL23501684 0.81 CYP2C9 (0.49) CYP2C9CYP2C19ALDH1A1LMNACA12
SCHEMBL1092469 0.80 CYP2C9 (0.51) CYP2C9CYP2C19ALDH1A1LMNASMN1; SMN2
SCHEMBL23501601 0.79 CYP2C9 (0.50) CYP2C9CYP2C19ALDH1A1LMNASMN1; SMN2
SCHEMBL31405471 0.79 CYP2C9 (0.44) CYP2C9CYP2C19ALDH1A1LMNACA12
SCHEMBL16421764 0.79 CYP2C9 (0.47) CYP2C9CYP2C19ALDH1A1LMNASMN1; SMN2
SCHEMBL19266065 0.76 CYP2C9 (0.44) CYP2C9CYP2C19ALDH1A1SMN1; SMN2CA12
SCHEMBL3725916 0.75 CYP2C9 (0.43) CYP2C9CYP2C19ALDH1A1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023210599-A1 COMPOUND SERVING AS DDR1 KINASE INHIBITOR, AND MEDICINE 日本新薬株式会社 2023-11-02 WO disclosed