SCHEMBL31405437

SCHEMBL31405437

C=Cc1cc(C(=O)OCC)cnc1CC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
CA12 O43570 3/20 0.41
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
CA7 P43166 3/20 0.41
CA9 Q16790 3/20 0.41
CA14 Q9ULX7 3/20 0.41
MAOB P27338 3/20 0.39
RAB9A P51151 2/20 0.39
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 3/20 0.39
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
DPP4 P27487 2/20 0.38
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAOA P21397 1/20 0.37
KMT2A Q03164 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26632523 0.95 CYP2C9 (0.43) CYP2C9CYP2C19CA12CA1CA2
SCHEMBL31405429 0.87 CYP2C9 (0.48) CYP2C9CYP2C19CA12CA1CA2
SCHEMBL23501684 0.85 CYP2C9 (0.49) CYP2C9CYP2C19CA12CA1CA2
SCHEMBL1092469 0.84 CYP2C9 (0.51) CYP2C9CYP2C19CA12CA1CA2
SCHEMBL31405471 0.83 CYP2C9 (0.44) CYP2C9CYP2C19CA12CA1CA2
SCHEMBL16421764 0.83 CYP2C9 (0.47) CYP2C9CYP2C19CA12CA1CA2
SCHEMBL19266065 0.81 CYP2C9 (0.44) CYP2C9CYP2C19CA12CA1CA2
SCHEMBL3725916 0.80 CYP2C9 (0.43) CYP2C9CYP2C19CA12CA1CA2
SCHEMBL26632464 0.79 CYP2C9 (0.41) CYP2C9CYP2C19CA12CA1CA2
SCHEMBL14466766 0.79 CYP2C9 (0.51) CYP2C9CYP2C19CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4516778-A1 COMPOUND SERVING AS DDR1 KINASE INHIBITOR, AND MEDICINE Nippon Shinyaku Co., Ltd. (JP) 2025-03-05 EP disclosed
CN-119421876-A Compounds and medicaments as DDR1 kinase inhibitors 日本新药株式会社 2025-02-11 CN disclosed