Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | PTGIR | P43119 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.30 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23295277 | 0.79 | MAOA (0.65) | MAOAMAOBPTGIRKMT2AAR | |
| SCHEMBL507295 | 0.79 | MAOA (0.53) | MAOAMAOBPTGIRKMT2AAR | |
| SCHEMBL5385654 | 0.79 | MAOA (0.53) | MAOAMAOBPTGIRKMT2ADDB1 | |
| SCHEMBL507543 | 0.79 | MAOA (0.53) | MAOAMAOBPTGIRKMT2AAR | |
| SCHEMBL26632615 | 0.79 | MAOA (0.53) | MAOAMAOBPTGIRKMT2AAR | |
| SCHEMBL26632622 | 0.79 | MAOA (0.53) | MAOAMAOBPTGIRKMT2AAR | |
| SCHEMBL31405196 | 0.78 | MAOA (0.56) | MAOAMAOBPTGIRKMT2AAR | |
| SCHEMBL17221461 | 0.77 | MAOA (0.50) | MAOAMAOBPTGIRKMT2AAR | |
| SCHEMBL2369246 | 0.77 | MAOA (0.50) | MAOAMAOBPTGIRKMT2AAR | |
| SCHEMBL26632592 | 0.75 | MAOA (0.49) | MAOAMAOBPTGIRKMT2AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250353942-A1 | Modified Pyridine-2,6-Bis(Phenylenephenolate) Complexes with Enhanced Solubility that are Useful as Catalyst Components for Olefin Polymerization | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2025-11-20 | — | — | US | disclosed |
| EP-4519330-A1 | MODIFIED PYRIDINE-2,6-BIS(PHENYLENEPHENOLATE) COMPLEXES WITH ENHANCED SOLUBILITY THAT ARE USEFUL AS CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION | ExxonMobil Chemical Patents Inc. (US) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023215696-A1 | MODIFIED PYRIDINE-2,6-BIS(PHENYLENEPHENOLATE) COMPLEXES WITH ENHANCED SOLUBILITY THAT ARE USEFUL AS CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2023-11-09 | — | — | WO | disclosed |